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IBS and Align ProbioticAlign probiotic has helped many people with IBS combat the constipation, diarrhea, abdominal discomfort, urgency, gas and bloating that Irritable Bowel Syndrome produces. Bet those symptoms sound familiar to some of you! The once-a-day capsule delivers 1 billion (1X109) live bacteria. Remember, not all probiotics work in the intestinal tract but the strain in Align does. Align probiotic contains Bifidobacterium infantis 35624 which is well researched and has been in a number of trials. It also contains milk and soy but is lactose free. An Irish trial involved 77 people with IBS. They were divided into 3 groups; one group received the Bifidobacterium infantis 35624 (1x1010) within a malted milk drink, the second group received a different probiotic in their drink and the third group received the plain malted milk drink with nothing added. The group that drank the milk containing Bifidobacterium infantis 35624 (that is the good bacteria in Align) had significantly less abdominal pain and discomfort, less bloating and distention of the intestines, and improved bowel movement function.1 The above trial used the bacteria at a slightly higher quantity than that found in Align probiotic but another trial2 was successful on a dosage of 1 hundred million (1x108) which is slightly LESS than found in Align so it appears as if the amount of live probiotic bacteria in 1 capsule is an effective amount for most people. Similar results have been recorded in a number of other studies so it does look as if Align is of benefit to many suffers in the fight against IBS. Click through if you would like to buy Align Daily Probiotic Supplement Capsules Or, you can read about my own experiences with Align probiotic and antibiotic diarrhea. Align testimonialThis probiotic star has many fans. You can read testimonials about Align written by other IBS sufferers at the bottom of the page through the above link. Quotes from the research on Align Probiotic"Clinical studies of probiotics in inflammatory bowel disease have proved disappointing, but beneficial effects in adults with irritable bowel syndrome have been reported with Bifidobacterium infantis 35624."3 "B. infantis 35624 at a dose of 1 x 10(8) cfu was significantly superior to placebo and all other bifidobacterium doses for the primary efficacy variable of abdominal pain as well as the composite score and scores for bloating, bowel dysfunction, incomplete evacuation, straining, and the passage of gas at the end of the 4-wk study." "CONCLUSIONS: B. infantis 35624 is a probiotic that specifically relieves many of the symptoms of IBS."2 "The data demonstrate that, although the intestinal epithelium is immunologically quiescent when it encounters B. infantis or L. salivarius, these commensal bacteria exert immunomodulatory effects on intestinal immune cells that mediate host responses to flagellin and enteric pathogens."4 This research is referring to strain 35624 "This study provides a rationale for the use of B. infantis 35624 for the treatment of gastrointestinal inflammation."5 "B infantis 35624 alleviates symptoms in IBS; this symptomatic response was associated with normalization of the ratio of an anti-inflammatory to a proinflammatory cytokine, suggesting an immune-modulating role for this organism, in this disorder.1 REFERENCES 1. O'Mahony L, McCarthy J, Kelly P, Hurley G, Luo F, Chen K, O'Sullivan GC, Kiely B, Collins JK, Shanahan F, Quigley EM. Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles. Gastroenterology. 2005 Mar;128(3):783-5. 2. Whorwell PJ, Altringer L, Morel J, Bond Y, Charbonneau D, O'Mahony L, Kiely B, Shanahan F, Quigley EM. Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome. Gastroenterology. 2007 Feb;132(2):813-6; discussion 816. 3. Vanderhoof JA. Probiotics in allergy management. J Pediatr Gastroenterol Nutr. 2008 Nov;47 Suppl 2:S38-40. 4. O'Hara AM, O'Regan P, Fanning A, O'Mahony C, Macsharry J, Lyons A, Bienenstock J, O'Mahony L, Shanahan F. Functional modulation of human intestinal epithelial cell responses by Bifidobacterium infantis and Lactobacillus salivarius. Immunology. 2006 Jun;118(2):202-15. 5. Sheil B, MacSharry J, O'Callaghan L, O'Riordan A, Waters A, Morgan J, Collins JK, O'Mahony L, Shanahan F. Role of interleukin (IL-10) in probiotic-mediated immune modulation: an assessment in wild-type and IL-10 knock-out mice. Clin Exp Immunol. 2006 May;144(2):273-80. Looking for info on probiotics?Top of Align Probiotic
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The information presented here is not intended to replace the advice of your doctor or medical professional. |
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to see if it gives you the relief it has some people. 
