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Bifidobacterium BifidumBifidobacterium bifidum is one member of the Bifidobacterium family that is believed to be strictly of human origin. There are others of this family that are strictly of animal origin and still others that can be found in both human and animal. Although B bifidum is not one of the largest numbered of the Bifidobacterium family to be found in adult humans (it makes up around 2% of the Bifidobacterium1) it is believed to somehow have a clear ecological advantage in adults1. Bifidobacterium bifidum has been shown to play an important part in the fermentation of Galactooligosaccharides2. Galacto-oligosaccharides (GOS) are the non–digestible, carbohydrate part of human milk. They are often added to things such as infant formula and milk products, granola etc. Galactooligosaccharides are selectively fermented by bacteria in the colon contributing to our good health. "Selectively fermented" means they are chosen before other substances. Coeliac diseaseCoeliac disease (CD) is characterized by an negative immune response to cereal-gluten proteins. Specific Bifidobacterium strains have been acknowledged for their anti-inflammatory and regulatory properties by inducing IL-10 production and regulating the Th1/Th2 balance. One study indicated that the intestinal microbiota of Coeliac disease patients could contribute to the Th1 pro-inflammatory effect of the disease, while strains of B longum and B bifidum could reverse these damaging effects4. Prevention of eczema or atopic dermatitis in infantsA once daily supplement, of Bifidobacterium bifidum BGN4, B lactis AD011, and Lactobacillus acidophilus AD031, starting at 4-8 weeks before delivery and continuing until 6 months after delivery had a beneficial effect in lowering the incidence of eczema or atopic dermatitis in babies born to families with history of allergic diseases3. What supplements is it in?Wakunaga of America Company - Kyo-Dophilus REFERENCES 1. Francesca Turroni, Elena Foroni, Paola Pizzetti, Vanessa Giubellini, Angela Ribbera, Paolo Merusi, Patrizio Cagnasso, Barbara Bizzarri, Gian Luigi de'Angelis, Fergus Shanahan, Douwe van Sinderen, and Marco Ventura. Exploring the Diversity of the Bifidobacterial Population in the Human Intestinal Tract. Appl Environ Microbiol. 2009 March; 75(6): 1534–1545. 2. Flore Depeint, George Tzortzis, Jelena Vulevic, Kerry I'Anson and Glenn R Gibson. Prebiotic evaluation of a novel galactooligosaccharide mixture produced by the enzymatic activity of Bifidobacterium bifidum NCIMB 41171, in healthy humans: a randomized, double-blind, crossover, placebo-controlled intervention study. American Journal of Clinical Nutrition, Vol. 87, No. 3, 785-791, March 2008 3. Kim JY, Kwon JH, Ahn SH, Lee SI, Han YS, Choi YO, Lee SY, Ahn KM, Ji GE. Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebo-controlled trial. Pediatr Allergy Immunol. 2009 Oct 14. [Epub ahead of print] 4. Marcela Medina, Giada De Palma, Carmen Ribes-Koninckx, Miguel Calabuig, and Yolanda Sanz. Bifidobacterium strains suppress in vitro the pro-inflammatory milieu triggered by the large intestinal microbiota of coeliac patients. J Inflamm (Lond). 2008; 5: 19. . Looking for info on probiotics?Top of Bifidobacterium Bifidum
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