Diflucan Yeast Infection
How Fast Does Diflucan Work?
Are you standing there eyeballing a tablet of Diflucan, yeast infection making you want to scream - or cry. Then the answer to how fast does Diflucan® work is the only question that matters.
Well, according to this 2005 study1, not as quickly as Gynazole-1® vaginal cream.
The study compared (amongst other things) the time it took for women to FIRST NOTICE an easing of vaginal itching, burning and irritation. Gynazole-1 won this race by a country mile.
The researchers found there was a "statistical difference" between the two treatments as early as 2 hours after taking/inserting them. At the 12 hour mark (after treatment) 44.4% of Gynazole-1 users had experienced "first relief" of symptoms compared with 29.1% of Diflucan users.
The doseage given in this trial were the standard one-dose treatment rates.
One group inserted a single application of approximately 5 g Gynazole-1 (butoconazole nitrate 2% Site Release® vaginal cream).
The other group took 1 Diflucan 150mg tablet (fluconazole 150 mg).
In this trial, two hours after the treatment, 12.3% of women who had inserted the Gynazole-1 vaginal cream reported the first feeling of relief of symptoms whilst only 2.5% of the women who had taken Diflucan experienced relief.
At 4 hours after treatment the figures were 25.9% (Gynazole-1) and 11.4% (Diflucan)
The study showed that symptoms began to disappear sooner after inserting a cream (topical therapy) than they did after taking a pill (systemic therapy). Evidently, this was a similar result to other studies. There are many considerations for you and your doctor to take into account but if rapid response is immportant then Diflucan as a yeast infection treatment is not your best choice.
As yeast infection is one of those things that can drive you CRAZY with burning or itching, this strikes me as a useful snippet of information for some women.
However, the time for ALL symptoms to completely disappear was about the same for both medications.
In an old 2000/2001 study2 of 1,992 women, 71% of the women said that quick relief of their symptoms was the most important thing to them. Anyone who has suffered a yeast infection can only nod their head in agreement at this.
So the answer to how long does it take Diflucan to work is - not as long as Gynazole!
REFERENCES (for Diflucan Yeast Infection)
1. Larry S. Seidmani, Campbell K. Skokos. An evaluation of butoconazole nitrate 2% Site Release® vaginal cream (Gynazole-1®) compared to fluconazole 150 mg tablets (Diflucan®) in the time to relief of symptoms in patients with vulvovaginal candidiasis. Infectious Diseases in Obstetrics and Gynecology, December 2005; 13(4): 197–206
2. Data on file: Gynazole-1 Clinical Experience Program; December 2000–April 2001: 2,176 participating physicians; 1,992 patients provided eligible responses.
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