Align Probiotic and IBS

Align probiotic has helped many people with IBS combat the constipation, diarrhea, abdominal discomfort, urgency, gas and bloating that Irritable Bowel Syndrome produces.

Bet those symptoms sound familiar to some of you!

The once-a-day capsule delivers 1 billion (1X109) live bacteria.

Remember, not all probiotics work in the intestinal tract but the strain in Align does.

Align Probiotic Supplement contains Bifidobacterium infantis 35624 which is well researched and has been in a number of trials.

It also contains milk and soy but is lactose free.

An Irish trial involved 77 people with IBS. They were divided into 3 groups; one group received the Bifidobacterium infantis 35624 (1x1010) within a malted milk drink, the second group received a different probiotic in their drink and the third group received the plain malted milk drink with nothing added.

The group that drank the milk containing Bifidobacterium infantis 35624 (that is the good bacteria in Align) had significantly less abdominal pain and discomfort, less bloating and distention of the intestines, and improved bowel movement function.1

The above trial used the bacteria at a slightly higher quantity than that found in Align probiotic but another trial2 was successful on a dosage of 1 hundred million (1x108) which is slightly LESS than found in Align so it appears as if the amount of live probiotic bacteria in 1 capsule is an effective amount for most people.

Similar results have been recorded in a number of other studies so it does look as if Align is of benefit to many suffers in the fight against IBS.

Click through if you would like to buy Align Daily Probiotic Supplement Capsules to see if it gives you the relief it has some people.

Or, if you live in the United Kingdom Align B. Infantis 35624 Probiotic Supplement 28 Count.

You can read about my own experiences with Align probiotic and antibiotic diarrhea.


Align testimonial

This probiotic star has many fans. Over six hundred 5 star reviews for Align on Amazon can't be bad! (It has over 900 reviews in total so many people like this trusted probiotic.)

Comments such as these Amazon verified purchasers abound:

  • "I suffer from IBS-C. It took about 3 days to see any results, but after 2 weeks I'm seeing at least one bm daily. "

  • "I've been using for IBS-D for a couple of months now, it has solved my problems. "

  • "I noticed an amazing difference after the first two weeks of use. Every afternoon, whether I had eaten lunch or not, my stomach would be bloated and painful. I could barely function. It was awful. But once I found Align - my whole quality of life changed for the better. I no longer have any afternoon symptoms."


Quotes from the research on Align Probiotic

"Clinical studies of probiotics in inflammatory bowel disease have proved disappointing, but beneficial effects in adults with irritable bowel syndrome have been reported with Bifidobacterium infantis 35624."3

"B. infantis 35624 at a dose of 1 x 10(8) cfu was significantly superior to placebo and all other bifidobacterium doses for the primary efficacy variable of abdominal pain as well as the composite score and scores for bloating, bowel dysfunction, incomplete evacuation, straining, and the passage of gas at the end of the 4-wk study."2

"CONCLUSIONS: B. infantis 35624 is a probiotic that specifically relieves many of the symptoms of IBS."2

"The data demonstrate that, although the intestinal epithelium is immunologically quiescent when it encounters B. infantis or L. salivarius, these commensal bacteria exert immunomodulatory effects on intestinal immune cells that mediate host responses to flagellin and enteric pathogens."4 This research is referring to strain 35624

"This study provides a rationale for the use of B. infantis 35624 for the treatment of gastrointestinal inflammation."5

"B infantis 35624 alleviates symptoms in IBS; this symptomatic response was associated with normalization of the ratio of an anti-inflammatory to a proinflammatory cytokine, suggesting an immune-modulating role for this organism, in this disorder.1

These all refer to the good bacteria in Align probiotic.


1. O'Mahony L, McCarthy J, Kelly P, Hurley G, Luo F, Chen K, O'Sullivan GC, Kiely B, Collins JK, Shanahan F, Quigley EM. Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles. Gastroenterology. 2005 Mar;128(3):783-5.

2. Whorwell PJ, Altringer L, Morel J, Bond Y, Charbonneau D, O'Mahony L, Kiely B, Shanahan F, Quigley EM. Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome. Gastroenterology. 2007 Feb;132(2):813-6; discussion 816.

3. Vanderhoof JA. Probiotics in allergy management. J Pediatr Gastroenterol Nutr. 2008 Nov;47 Suppl 2:S38-40.

4. O'Hara AM, O'Regan P, Fanning A, O'Mahony C, Macsharry J, Lyons A, Bienenstock J, O'Mahony L, Shanahan F. Functional modulation of human intestinal epithelial cell responses by Bifidobacterium infantis and Lactobacillus salivarius. Immunology. 2006 Jun;118(2):202-15.

5. Sheil B, MacSharry J, O'Callaghan L, O'Riordan A, Waters A, Morgan J, Collins JK, O'Mahony L, Shanahan F. Role of interleukin (IL-10) in probiotic-mediated immune modulation: an assessment in wild-type and IL-10 knock-out mice. Clin Exp Immunol. 2006 May;144(2):273-80.