Diflucan yeast infection - if you've got a vaginal yeast infection then the answer to how fast does Diflucan® work is the only question that matters.
Well, according to this 2005 study1, not as quickly as Gynazole-1® vaginal cream.
Gynazole and Diflucan (fluconazole) are both prescription medicines to be got through your doctor.
The study compared (amongst other things) the time it took for women to FIRST NOTICE an easing of vaginal itching, burning and irritation. Gynazole-1 won this race by a country mile.
The researchers found there was a "statistical difference" between the two treatments as early as 2 hours after taking/inserting them. At the 12 hour mark (after treatment) 44.4% of Gynazole-1 users had experienced "first relief" of symptoms compared with 29.1% of Diflucan yeast infection users.
The doseage given in this trial were the standard one-dose treatment rates.
One group inserted a single application of approximately 5 g Gynazole-1 (butoconazole nitrate 2% Site Release® vaginal cream).
The other group took 1 Diflucan 150mg tablet (fluconazole 150 mg).In this trial, two hours after the treatment, 12.3% of women who had inserted the Gynazole-1 vaginal cream reported the first feeling of relief of symptoms whilst only 2.5% of the women who had taken Diflucan experienced relief.
At 4 hours after treatment the figures were 25.9% (Gynazole-1) and 11.4% (Diflucan)
The study showed that symptoms began to disappear sooner after inserting a cream (topical therapy) than they did after taking a pill (systemic therapy). Evidently, this was a similar result to other studies. There are many considerations for you and your doctor to take into account but if rapid response is important then Diflucan yeast infection treatment is not your best choice.
As yeast infection is one of those things that can drive you CRAZY with burning or itching, this strikes me as a useful snippet of information for some women.
However, the time for ALL symptoms to completely disappear was about the same for both medications.
In an old 2000/2001 study2 of 1,992 women, 71% of the women said that quick relief of their symptoms was the most important thing to them. Anyone who has suffered a yeast infection can only nod their head in agreement at this.
So the answer to how long does it take Diflucan to work is - not as long as Gynazole!
Whatever your choice, follow up Diflucan thrush treatment with Fem-Dophilus a probiotic capsule that will help to keep the yeast infection away.
REFERENCES (for Diflucan Yeast Infection)
1. Larry S. Seidmani, Campbell K. Skokos. An evaluation of butoconazole nitrate 2% Site Release® vaginal cream (Gynazole-1®) compared to fluconazole 150 mg tablets (Diflucan®) in the time to relief of symptoms in patients with vulvovaginal candidiasis. Infectious Diseases in Obstetrics and Gynecology, December 2005; 13(4): 197—206
2. Data on file: Gynazole-1 Clinical Experience Program; December 2000—April 2001: 2,176 participating physicians; 1,992 patients provided eligible responses.
Measures pH in the correct range for women's health